The Screening models for antiepileptic drugs: A Review

Considering the prevalence of epilepsy and problems associated with currently available antiepileptic drugs like side effects, resistance, safety issue high cost, herbal medicine fewer complications could be very appropriate alternative. Therefore in present study, we have examined properties ethanolic extract leaves mice using maximal electroshock seizers (MES)test, Pentylenetetrazole (PTZ), induced seizures, strychnine convulsion, Isoniazid-induced convulsions, Picrotoxin-induced Kainic acid (KA) model etc.There is increased concern on agents for disease modification prevention. To solve these unmet needs, research scientist must a thorough knowledge animal models so that he can pick up best his research. In this article, are reviewing diversity their implications drug discovery.
 Keywords: Epilepsy, model,